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Extensive experience of profiling microbiome composition and functions

All good analysis starts with a good question; we help formulate a research hypothesis that can be soundly tested and adequately powered to give reliable results.  We help you frame the correct question and apply the appropriate methods and technology to help you gain the answers.

  • Amplicon Sequencing – “What microbes are there?”
  • Comparative Genomics – “How are they different?”
  • Metagenomics – “What can they do?”
  • Metatranscriptomics – “What are they doing right now?”

Our extensive experience covers profiling microbiome composition and functions from phylogenetic markers (16S rRNA gene/transcript, ITS or other taxonomic markers) and shotgun meta-genomic/transcriptomic sequencing.

With our custom pipeline we can provide species-level classification for 16S rRNA gene sequences wherever possible from Amplicon Sequence Variants. We provide compositionally appropriate exploratory data analysis and statistical comparison in addition to strain level resolution and high throughput functional annotation with state-of-the-art bioinformatic approaches.

If you have specific genomes you wish to investigate, our team has considerable experience in comparative genomics, with the ability to identify antibiotic resistance features, virulence factors or other genes of interest with a high degree of accuracy.

Study Design

Sample Processing

Sequencing

Biostatistical and Bioinformatic Analysis

Publication/Patent Ready Outputs